Because everyone’s skin is different, there’s no “best” concentration of tretinoin cream. Most people that use retinoin cream, whether for acne prevention or in an anti-aging cream, use a variety of different concentrations over the years before selecting a cream that best suits their skin.
In the US, most doctors start by prescribing patients .005% (low strength) tretinoin cream, which provides an optimal combination of effectiveness and tolerable side effects for most patients. If this cream isn’t effective, your doctor might recommend switching to a stronger tretinoin cream.
If side effects such as skin irritation, redness or peeling occur, your doctor might recommend switching to a lower strength tretinoin cream, using the cream every less frequently or using alcohol-free moisturizer in combination with the tretinoin cream.
Finally, it’s important to remember that tretinoin often causes the most significant side effects during the first two to six weeks of use, meaning you may experience some temporary side effects even at the correct concentration and dosage.
Learn More About Tretinoin
Are you considering tretinoin as an acne treatment? Our complete guide to using tretinoin for acne covers every aspect of treating acne with tretinoin, from applying the cream properly to maximizing your results over the long term.